6PML

Crystal Structure of EcDsbA in complex benzyl ether 23

Summary for 6PML

Entry DOI	10.2210/pdb6pml/pdb
Descriptor	Thiol:disulfide interchange protein DsbA, DI(HYDROXYETHYL)ETHER, [6-(benzyloxy)-1-benzofuran-3-yl]acetic acid, ... (5 entities in total)
Functional Keywords	disulfide oxidoreductase, redox protein, oxidoreductase-inhibitor complex, oxidoreductase, oxidoreductase/inhibitor
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	2
Total formula weight	42762.01
Authors	Ilyichova, O.V.,Scanlon, M.J. (deposition date: 2019-07-02, release date: 2019-11-06, Last modification date: 2023-10-11)
Primary citation	Duncan, L.F.,Wang, G.,Ilyichova, O.V.,Scanlon, M.J.,Heras, B.,Abbott, B.M. The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors. Molecules, 24:-, 2019 Cited by PubMed: 31635355 DOI: 10.3390/molecules24203756 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation