6PML

Crystal Structure of EcDsbA in complex benzyl ether 23

6PML の概要

• エントリーDOI: 10.2210/pdb6pml/pdb
• 分子名称: Thiol:disulfide interchange protein DsbA, DI(HYDROXYETHYL)ETHER, [6-(benzyloxy)-1-benzofuran-3-yl]acetic acid, ... (5 entities in total)
• 機能のキーワード: disulfide oxidoreductase, redox protein, oxidoreductase-inhibitor complex, oxidoreductase, oxidoreductase/inhibitor
• 由来する生物種: Escherichia coli (strain K12)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 42762.01

構造登録者

Ilyichova, O.V.,Scanlon, M.J. (登録日: 2019-07-02, 公開日: 2019-11-06, 最終更新日: 2023-10-11)

• 主引用文献: Duncan, L.F.,Wang, G.,Ilyichova, O.V.,Scanlon, M.J.,Heras, B.,Abbott, B.M.; The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors.; Molecules, 24:-, 2019; PubMed: 31635355; DOI: 10.3390/molecules24203756

実験手法

X-RAY DIFFRACTION (2 Å)