6PL9

Adduct formed after 1 month in the reaction of dichlorido(1,3-dimethylbenzimidaz ol-2-ylidene)(eta5-pentamethylcyclopentadienyl)rhodium(III) with HEWL

6PL9 の概要

• エントリーDOI: 10.2210/pdb6pl9/pdb
• 分子名称: Lysozyme, dichloro[(1,2,3,4,5-eta)-pentamethylcyclopentadienyl]rhodium, 2-(1-chloranyl-2,3,4,5,6-pentamethyl-1$l^{7}-rhodapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexan-1-yl)-1,3-dimethyl-benzimidazole, ... (5 entities in total)
• 機能のキーワード: metal-based, anticancer, ruthenium, nhc, carbene, lysozyme, metallodrug, benzimidazole, dimethylbenzimidazole, hydrolase
• 由来する生物種: Gallus gallus (Chicken)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15082.96

構造登録者

Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (登録日: 2019-06-30, 公開日: 2020-11-25, 最終更新日: 2023-10-11)

• 主引用文献: Sullivan, M.P.,Cziferszky, M.,Tolbatov, I.,Truong, D.,Mercadante, D.,Re, N.,Gust, R.,Goldstone, D.C.,Hartinger, C.; Probing the Paradigm of Promiscuity for N-Heterocyclic Carbene Complexes and their Protein Adduct Formation.; Angew.Chem.Int.Ed.Engl., 2021; PubMed: 34196088; DOI: 10.1002/anie.202106906

実験手法

X-RAY DIFFRACTION (1.2 Å)