6PKI

Zebrafish N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain (C56S C230S) in complex with N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) and mannose 6-phosphate (M6P)

6PKI の概要

• エントリーDOI: 10.2210/pdb6pki/pdb
• 分子名称: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: uncovering enzyme, mannose 6-phosphate, glycosidase, n-acetylglucosamine, hydrolase
• 由来する生物種: Danio rerio (Zebrafish)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 140530.50

構造登録者

Gorelik, A.,Illes, K.,Nagar, B. (登録日: 2019-06-29, 公開日: 2020-02-19, 最終更新日: 2023-10-11)

• 主引用文献: Gorelik, A.,Illes, K.,Nagar, B.; Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme.; Structure, 28:426-436.e3, 2020; PubMed: 32109365; DOI: 10.1016/j.str.2020.02.001

実験手法

X-RAY DIFFRACTION (2.293 Å)