Summary for 6PFK
| Entry DOI | 10.2210/pdb6pfk/pdb |
| Descriptor | PHOSPHOFRUCTOKINASE, 2-PHOSPHOGLYCOLIC ACID (3 entities in total) |
| Functional Keywords | transferase, kinase, glycolysis |
| Biological source | Geobacillus stearothermophilus |
| Cellular location | Cytoplasm: P00512 |
| Total number of polymer chains | 4 |
| Total formula weight | 137295.53 |
| Authors | Evans, P.R.,Schirmer, T.,Auer, M. (deposition date: 1996-01-04, release date: 1996-07-11, Last modification date: 2024-03-13) |
| Primary citation | Schirmer, T.,Evans, P.R. Structural basis of the allosteric behaviour of phosphofructokinase. Nature, 343:140-145, 1990 Cited by PubMed Abstract: Comparison between the crystal structures of low- and high-affinity forms of phosphofructokinase shows a close coupling between the change of quaternary structure and local changes triggered by binding of the allosteric effectors. These concerted changes link all the substrate and effector sites in the tetramer, and explain the change of affinity for the cooperative substrate. PubMed: 2136935DOI: 10.1038/343140a0 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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