6PF0

SOLID-STATE NMR STRUCTURE OF PISCIDIN 1 IN ALIGNED 4:1 PHOSPHATIDYLCHOLINE/CHOLESTEROL LIPID BILAYERS

6PF0 の概要

• エントリーDOI: 10.2210/pdb6pf0/pdb
• NMR情報: BMRB: 30616
• 分子名称: Moronecidin (1 entity in total)
• 機能のキーワード: antimicrobial peptide, anticancer peptide, anti hiv-1, cationic, amphipathic, histidine rich, helical, lipid bilayers, bacterial cell membrane mimic, antimicrobial protein
• 由来する生物種: Morone saxatilis (Striped bass)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2577.09

構造登録者

Greenwood, A.I.,Cairns, L.S.,Fu, R.,Cotten, M.L. (登録日: 2019-06-21, 公開日: 2019-10-16, 最終更新日: 2023-06-14)

• 主引用文献: Comert, F.,Greenwood, A.,Maramba, J.,Acevedo, R.,Lucas, L.,Kulasinghe, T.,Cairns, L.S.,Wen, Y.,Fu, R.,Hammer, J.,Blazyk, J.,Sukharev, S.,Cotten, M.L.,Mihailescu, M.; The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels.; J.Biol.Chem., 294:18557-18570, 2019; PubMed: 31619519; DOI: 10.1074/jbc.RA119.010232

実験手法

SOLID-STATE NMR