6PCQ
E. coli 50S ribosome bound to VM2
Summary for 6PCQ
Entry DOI | 10.2210/pdb6pcq/pdb |
EMDB information | 20304 |
Descriptor | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... (8 entities in total) |
Functional Keywords | e. coli ribosome, streptogramin a analog, antibiotics, ribosome |
Biological source | Escherichia coli More |
Total number of polymer chains | 7 |
Total formula weight | 1085622.35 |
Authors | Pellegrino, J.,Lee, D.J.,Fraser, J.S.,Seiple, I.B. (deposition date: 2019-06-18, release date: 2020-06-17, Last modification date: 2020-10-07) |
Primary citation | Li, Q.,Pellegrino, J.,Lee, D.J.,Tran, A.A.,Chaires, H.A.,Wang, R.,Park, J.E.,Ji, K.,Chow, D.,Zhang, N.,Brilot, A.F.,Biel, J.T.,van Zundert, G.,Borrelli, K.,Shinabarger, D.,Wolfe, C.,Murray, B.,Jacobson, M.P.,Muhle, E.,Chesneau, O.,Fraser, J.S.,Seiple, I.B. Synthetic group A streptogramin antibiotics that overcome Vat resistance. Nature, 586:145-150, 2020 Cited by PubMed: 32968273DOI: 10.1038/s41586-020-2761-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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