6PAX

CRYSTAL STRUCTURE OF THE HUMAN PAX-6 PAIRED DOMAIN-DNA COMPLEX REVEALS A GENERAL MODEL FOR PAX PROTEIN-DNA INTERACTIONS

Summary for 6PAX

• Entry DOI: 10.2210/pdb6pax/pdb
• Descriptor: 26 NUCLEOTIDE DNA, HOMEOBOX PROTEIN PAX-6, ... (4 entities in total)
• Functional Keywords: pax, paired domain, transcription, protein-dna interactions, gene regulation-dna complex, gene regulation/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P26367
• Total number of polymer chains: 3
• Total formula weight: 30494.86

Authors

Xu, H.E.,Rould, M.A.,Xu, W.,Epstein, J.A.,Maas, R.L.,Pabo, C.O. (deposition date: 1999-04-22, release date: 1999-07-13, Last modification date: 2024-04-03)

• Primary citation: Xu, H.E.,Rould, M.A.,Xu, W.,Epstein, J.A.,Maas, R.L.,Pabo, C.O.; Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding.; Genes Dev., 13:1263-1275, 1999; PubMed: 10346815

Experimental method

X-RAY DIFFRACTION (2.5 Å)