6PAT
Active State of Manduca sexta soluble Guanylate Cyclase
Summary for 6PAT
Entry DOI | 10.2210/pdb6pat/pdb |
EMDB information | 20283 |
Descriptor | Soluble guanylyl cyclase alpha-1 subunit, Soluble guanylyl cyclase beta-1 subunit, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total) |
Functional Keywords | nitric oxide, cyclase, h-nox, stimulator, signaling protein |
Biological source | Manduca sexta (Tobacco hawkmoth) More |
Total number of polymer chains | 2 |
Total formula weight | 147397.21 |
Authors | Yokom, A.L.,Horst, B.G.,Marletta, M.A.,Hurley, J.H. (deposition date: 2019-06-11, release date: 2019-10-23, Last modification date: 2024-03-20) |
Primary citation | Horst, B.G.,Yokom, A.L.,Rosenberg, D.J.,Morris, K.L.,Hammel, M.,Hurley, J.H.,Marletta, M.A. Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy. Elife, 8:-, 2019 Cited by PubMed: 31566566DOI: 10.7554/eLife.50634 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.8 Å) |
Structure validation
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