6P9N
CRYSTAL STRUCTURE OF HIV-1 LM/HT CLADE A/E CRF01 GP120 CORE IN COMPLEX WITH (S)-MCG-IV-210.
Summary for 6P9N
Entry DOI | 10.2210/pdb6p9n/pdb |
Descriptor | HIV-1 LM/HT Clade A/E CRF01 gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, (3S)-N~1~-(2-aminoethyl)-N~3~-(4-chloro-3-fluorophenyl)piperidine-1,3-dicarboxamide, ... (5 entities in total) |
Functional Keywords | hiv-1 gp120, clade a/e cf01, viral protein, immune system |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 42259.93 |
Authors | Tolbert, W.D.,Sherburn, R.,Pazgier, M. (deposition date: 2019-06-10, release date: 2019-10-23, Last modification date: 2023-10-11) |
Primary citation | Ding, S.,Grenier, M.C.,Tolbert, W.D.,Vezina, D.,Sherburn, R.,Richard, J.,Prevost, J.,Chapleau, J.P.,Gendron-Lepage, G.,Medjahed, H.,Abrams, C.,Sodroski, J.,Pazgier, M.,Smith 3rd, A.B.,Finzi, A. A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity. J.Virol., 93:-, 2019 Cited by PubMed: 31554684DOI: 10.1128/JVI.01325-19 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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