6P9N

CRYSTAL STRUCTURE OF HIV-1 LM/HT CLADE A/E CRF01 GP120 CORE IN COMPLEX WITH (S)-MCG-IV-210.

6P9N の概要

• エントリーDOI: 10.2210/pdb6p9n/pdb
• 分子名称: HIV-1 LM/HT Clade A/E CRF01 gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, (3S)-N~1~-(2-aminoethyl)-N~3~-(4-chloro-3-fluorophenyl)piperidine-1,3-dicarboxamide, ... (5 entities in total)
• 機能のキーワード: hiv-1 gp120, clade a/e cf01, viral protein, immune system
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42259.93

構造登録者

Tolbert, W.D.,Sherburn, R.,Pazgier, M. (登録日: 2019-06-10, 公開日: 2019-10-23, 最終更新日: 2023-10-11)

• 主引用文献: Ding, S.,Grenier, M.C.,Tolbert, W.D.,Vezina, D.,Sherburn, R.,Richard, J.,Prevost, J.,Chapleau, J.P.,Gendron-Lepage, G.,Medjahed, H.,Abrams, C.,Sodroski, J.,Pazgier, M.,Smith 3rd, A.B.,Finzi, A.; A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity.; J.Virol., 93:-, 2019; PubMed: 31554684; DOI: 10.1128/JVI.01325-19

実験手法

X-RAY DIFFRACTION (2.65 Å)