6OZH

Crystal structure of Ciona intestinalis (Ci) Endonuclease V in complex with a 24mer DNA containing an inosine followed by a ribo-adenosine

Summary for 6OZH

• Entry DOI: 10.2210/pdb6ozh/pdb
• Descriptor: endonuclease V isoform X2, DNA/RNA (5'-D(P*CP*GP*GP*TP*AP*AP*CP*CP*GP*I)-R(P*A)-D(P*TP*AP*TP*GP*CP*AP*GP*CP*AP*TP*TP*TP*C)-3'), CALCIUM ION (3 entities in total)
• Functional Keywords: nucleic acid hydrolysis, rna recognition, metal ion dependent catalysis, dna damage, adenosine deamination, hydrolase
• Biological source: Ciona intestinalis (Transparent sea squirt); More
• Total number of polymer chains: 8
• Total formula weight: 140780.88

Authors

Samara, N.L.,Yang, W. (deposition date: 2019-05-15, release date: 2019-09-04, Last modification date: 2024-03-13)

• Primary citation: Wu, J.,Samara, N.L.,Kuraoka, I.,Yang, W.; Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.; Mol.Cell, 76:44-, 2019; PubMed: 31444105; DOI: 10.1016/j.molcel.2019.06.046

Experimental method

X-RAY DIFFRACTION (3.026 Å)