6OS9

human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in canonical conformation (C state)

Summary for 6OS9

• Entry DOI: 10.2210/pdb6os9/pdb
• EMDB information: 20180
• Descriptor: Neurotensin receptor type 1, JMV449, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (6 entities in total)
• Functional Keywords: gpcr, g-protein, complex, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 162891.89

Authors

Kato, H.E.,Zhang, Y.,Kobilka, B.K.,Skiniotis, G. (deposition date: 2019-05-01, release date: 2019-07-10, Last modification date: 2019-12-18)

• Primary citation: Kato, H.E.,Zhang, Y.,Hu, H.,Suomivuori, C.M.,Kadji, F.M.N.,Aoki, J.,Krishna Kumar, K.,Fonseca, R.,Hilger, D.,Huang, W.,Latorraca, N.R.,Inoue, A.,Dror, R.O.,Kobilka, B.K.,Skiniotis, G.; Conformational transitions of a neurotensin receptor 1-Gi1complex.; Nature, 572:80-85, 2019; PubMed: 31243364; DOI: 10.1038/s41586-019-1337-6

Experimental method

ELECTRON MICROSCOPY (3 Å)