human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in canonical conformation (C state)

Summary for 6OS9

EMDB information20180
DescriptorNeurotensin receptor type 1, JMV449, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (6 entities in total)
Functional Keywordsgpcr, g-protein, complex, signaling protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains6
Total molecular weight162891.89
Kato, H.E.,Zhang, Y.,Kobilka, B.K.,Skiniotis, G. (deposition date: 2019-05-01, release date: 2019-07-10, Last modification date: 2019-08-14)
Primary citation
Kato, H.E.,Zhang, Y.,Hu, H.,Suomivuori, C.M.,Kadji, F.M.N.,Aoki, J.,Krishna Kumar, K.,Fonseca, R.,Hilger, D.,Huang, W.,Latorraca, N.R.,Inoue, A.,Dror, R.O.,Kobilka, B.K.,Skiniotis, G.
Conformational transitions of a neurotensin receptor 1-Gi1complex.
Nature, 572:80-85, 2019
PubMed: 31243364 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-019-1337-6
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers50 0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures