6OOO

Crystal structure of HIV-1 LM/HT Clade A/E CRF01 gp120 core in complex with (S)-MCG-IV-226.

6OOO の概要

• エントリーDOI: 10.2210/pdb6ooo/pdb
• 分子名称: HIV-1 LM/HT Clade A/E CRF01 gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, (3S,5R)-5-amino-N~3~-(4-chloro-3-fluorophenyl)-N~1~-propylpiperidine-1,3-dicarboxamide, ... (5 entities in total)
• 機能のキーワード: hiv-1 gp120, clade a/e cf01, viral protein, viral protein-inhibitor complex, viral protein/inhibitor
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42273.96

構造登録者

Tolbert, W.D.,Sherburn, R.,Pazgier, M. (登録日: 2019-04-23, 公開日: 2020-03-11, 最終更新日: 2023-10-11)

• 主引用文献: Grenier, M.C.,Ding, S.,Vezina, D.,Chapleau, J.P.,Tolbert, W.D.,Sherburn, R.,Schon, A.,Somisetti, S.,Abrams, C.F.,Pazgier, M.,Finzi, A.,Smith 3rd, A.B.; Optimization of Small Molecules That Sensitize HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity.; Acs Med.Chem.Lett., 11:371-378, 2020; PubMed: 32184972; DOI: 10.1021/acsmedchemlett.9b00445

実験手法

X-RAY DIFFRACTION (2.4 Å)