6ONM

Crystal Structure of (+)-Limonene Synthase Complexed with 8,9-Difluorolinalyl Diphosphate

6ONM の概要

• エントリーDOI: 10.2210/pdb6onm/pdb
• 分子名称: (+)-limonene synthase, MANGANESE (II) ION, (3R)-8-fluoro-7-(fluoromethyl)-3-methylocta-1,6-dien-3-yl trihydrogen diphosphate, ... (4 entities in total)
• 機能のキーワード: terpene synthase, enantiomer, terpene synthase fold, monoterpene, fluoro analog, metal binding, lyase
• 由来する生物種: Citrus sinensis (Sweet orange)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 70956.22

構造登録者

Prem Kumar, R.,Morehouse, B.R.,Yu, Q.,Oprian, D.D. (登録日: 2019-04-22, 公開日: 2019-09-04, 最終更新日: 2023-10-11)

• 主引用文献: Morehouse, B.R.,Kumar, R.P.,Matos, J.O.,Yu, Q.,Bannister, A.,Malik, K.,Temme, J.S.,Krauss, I.J.,Oprian, D.D.; Direct Evidence of an Enzyme-Generated LPP Intermediate in (+)-Limonene Synthase Using a Fluorinated GPP Substrate Analog.; Acs Chem.Biol., 14:2035-2043, 2019; PubMed: 31433159; DOI: 10.1021/acschembio.9b00514

実験手法

X-RAY DIFFRACTION (2.7 Å)