6OLT

Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C12-crypto Acyl Carrier Protein, AcpP

Summary for 6OLT

• Entry DOI: 10.2210/pdb6olt/pdb
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... (4 entities in total)
• Functional Keywords: ketosynthase, ks, acpp, beta-ketoacyl-acyl carrier protein synthase, beta-ketoacyl-acp synthase, acyl carrier protein, transferase-transport protein complex, transferase
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 2
• Total formula weight: 52258.69

Authors

Mindrebo, J.T.,Kim, W.E.,Bartholow, T.G.,Chen, A.,Davis, T.D.,La Clair, J.,Burkart, M.D.,Noel, J.P. (deposition date: 2019-04-17, release date: 2020-04-22, Last modification date: 2023-10-11)

• Primary citation: Mindrebo, J.T.,Patel, A.,Kim, W.E.,Davis, T.D.,Chen, A.,Bartholow, T.G.,La Clair, J.J.,McCammon, J.A.,Noel, J.P.,Burkart, M.D.; Gating mechanism of elongating beta-ketoacyl-ACP synthases.; Nat Commun, 11:1727-1727, 2020; PubMed: 32265440; DOI: 10.1038/s41467-020-15455-x

Experimental method

X-RAY DIFFRACTION (2.35 Å)