6OLT

Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C12-crypto Acyl Carrier Protein, AcpP

6OLT の概要

• エントリーDOI: 10.2210/pdb6olt/pdb
• 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, N-[2-(dodecanoylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... (4 entities in total)
• 機能のキーワード: ketosynthase, ks, acpp, beta-ketoacyl-acyl carrier protein synthase, beta-ketoacyl-acp synthase, acyl carrier protein, transferase-transport protein complex, transferase
• 由来する生物種: Escherichia coli (strain K12); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52258.69

構造登録者

Mindrebo, J.T.,Kim, W.E.,Bartholow, T.G.,Chen, A.,Davis, T.D.,La Clair, J.,Burkart, M.D.,Noel, J.P. (登録日: 2019-04-17, 公開日: 2020-04-22, 最終更新日: 2023-10-11)

• 主引用文献: Mindrebo, J.T.,Patel, A.,Kim, W.E.,Davis, T.D.,Chen, A.,Bartholow, T.G.,La Clair, J.J.,McCammon, J.A.,Noel, J.P.,Burkart, M.D.; Gating mechanism of elongating beta-ketoacyl-ACP synthases.; Nat Commun, 11:1727-1727, 2020; PubMed: 32265440; DOI: 10.1038/s41467-020-15455-x

実験手法

X-RAY DIFFRACTION (2.35 Å)