6OL8

Crystal structure of NDM-12 metallo-beta-lactamase in complex with hydrolyzed ampicillin

Summary for 6OL8

• Entry DOI: 10.2210/pdb6ol8/pdb
• Related: 6OGO
• Descriptor: Metallo-beta-lactamase NDM-12, ZINC ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: metallo-beta-lactamase, ndm, hydrolase, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 52677.47

Authors

Raczynska, J.E.,Imiolczyk, B.,Jaskolski, M. (deposition date: 2019-04-16, release date: 2020-04-22, Last modification date: 2023-10-11)

• Primary citation: Raczynska, J.E.,Imiolczyk, B.,Komorowska, M.,Sliwiak, J.,Czyrko-Horczak, J.,Brzezinski, K.,Jaskolski, M.; Flexible loops of New Delhi metallo-beta-lactamase modulate its activity towards different substrates.; Int.J.Biol.Macromol., 158:104-115, 2020; PubMed: 32353499; DOI: 10.1016/j.ijbiomac.2020.04.219

Experimental method

X-RAY DIFFRACTION (2.1 Å)