6OKK

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit

Summary for 6OKK

• Entry DOI: 10.2210/pdb6okk/pdb
• EMDB information: 2660
• Descriptor: 18S ribosomal RNA, 40S ribosomal protein S7, 40S ribosomal protein S15A, ... (36 entities in total)
• Functional Keywords: protein synthesis, antimalarial drug, ribosome, ribosome-inhibitor complex, ribosome/inhibitor
• Biological source: Plasmodium falciparum (isolate 3D7); More
• Total number of polymer chains: 33
• Total formula weight: 1263059.92

Authors

Wong, W.,Scheres, S.H.W. (deposition date: 2019-04-13, release date: 2019-05-22, Last modification date: 2020-01-08)

• Primary citation: Wong, W.,Bai, X.C.,Brown, A.,Fernandez, I.S.,Hanssen, E.,Condron, M.,Tan, Y.H.,Baum, J.,Scheres, S.H.; Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.; Elife, 3:-, 2014; PubMed: 24913268; DOI: 10.7554/eLife.03080

Experimental method

ELECTRON MICROSCOPY (3.3 Å)