6OKK

Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit

Summary for 6OKK

EMDB information2660
Descriptor18S ribosomal RNA, 40S ribosomal protein S3a, 40S ribosomal protein SA, ... (36 entities in total)
Functional Keywordsprotein synthesis, antimalarial drug, ribosome, ribosome-inhibitor complex, ribosome/inhibitor
Biological sourcePlasmodium falciparum (isolate 3D7)
Total number of polymer chains33
Total molecular weight1263059.92
Authors
Wong, W.,Scheres, S.H.W. (deposition date: 2019-04-13, release date: 2019-05-22)
Primary citation
Wong, W.,Schere, S.H.W.
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone4 4.2% 14.2% 0.39MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures