6OA7

Horse liver L57F alcohol dehydrogenase E complexed with NAD and trifluoroethanol

6OA7 の概要

• エントリーDOI: 10.2210/pdb6oa7/pdb
• 関連するPDBエントリー: 4DXH 5kcz 6o91
• 分子名称: Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
• 機能のキーワード: alcohol dehydrogenase, nad, 2, 2-trifluoroethanol, leu57 to phe57 substitution, horse liver e enzyme, oxidoreductase
• 由来する生物種: Equus caballus (Horse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 82154.01

構造登録者

Plapp, B.V. (登録日: 2019-03-15, 公開日: 2019-04-03, 最終更新日: 2023-10-11)

• 主引用文献: Kim, K.,Plapp, B.V.; Substitutions of Amino Acid Residues in the Substrate Binding Site of Horse Liver Alcohol Dehydrogenase Have Small Effects on the Structures but Significantly Affect Catalysis of Hydrogen Transfer.; Biochemistry, 59:862-879, 2020; PubMed: 31994873; DOI: 10.1021/acs.biochem.9b01074

実験手法

X-RAY DIFFRACTION (1.1 Å)