6O85

Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens

Summary for 6O85

Entry DOI	10.2210/pdb6o85/pdb
EMDB information	0651
Descriptor	Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... (9 entities in total)
Functional Keywords	eukaryotic translation initiation factor 2b, eukaryotic translation initiation factor 2, translation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	13
Total formula weight	615216.68
Authors	Nguyen, H.C.,Kenner, L.R.,Frost, A.S. (deposition date: 2019-03-08, release date: 2019-05-15, Last modification date: 2024-03-13)
Primary citation	Kenner, L.R.,Anand, A.A.,Nguyen, H.C.,Myasnikov, A.G.,Klose, C.J.,McGeever, L.A.,Tsai, J.C.,Miller-Vedam, L.E.,Walter, P.,Frost, A. eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. Science, 364:491-495, 2019 Cited by PubMed: 31048491 DOI: 10.1126/science.aaw2922 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.03 Å)

Structure validation