6O78

Crystal structure of Csm1-Csm4 cassette in complex with pppApApA

6O78 の概要

• エントリーDOI: 10.2210/pdb6o78/pdb
• 分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, RNA (5'-D(*(ATP))-R(P*AP*A)-3'), ... (4 entities in total)
• 機能のキーワード: type iii-a crispr-cas system, csm1-csm4 cassette in complex with pppapapa, immune system, immune system-dna complex, immune system-rna complex, immune system/rna
• 由来する生物種: Thermococcus onnurineus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 123264.15

構造登録者

Jia, N.,Patel, D.J. (登録日: 2019-03-07, 公開日: 2019-07-31, 最終更新日: 2023-10-11)

• 主引用文献: Jia, N.,Jones, R.,Sukenick, G.,Patel, D.J.; Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.; Mol.Cell, 75:933-943.e6, 2019; PubMed: 31326272; DOI: 10.1016/j.molcel.2019.06.013

実験手法

X-RAY DIFFRACTION (2.8 Å)