6O55

Crystal Structure of N5-carboxyaminoimidazole ribonucleotide mutase (PurE) from Legionella pneumophila

6O55 の概要

• エントリーDOI: 10.2210/pdb6o55/pdb
• 分子名称: N5-carboxyaminoimidazole ribonucleotide mutase, 1,2-ETHANEDIOL, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: ssgcid, mutase, carboxylase, phosphorobosylaminoimidazole carboxylase, structural genomics, seattle structural genomics center for infectious disease, isomerase
• 由来する生物種: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 75018.15

構造登録者

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2019-03-01, 公開日: 2019-03-13, 最終更新日: 2024-05-29)

• 主引用文献: Belfon, K.K.J.,Sharma, N.,Zigweid, R.,Bolejack, M.,Davies, D.,Edwards, T.E.,Myler, P.J.,French, J.B.; Structure-Guided Discovery of N 5 -CAIR Mutase Inhibitors.; Biochemistry, 62:2587-2596, 2023; PubMed: 37552766; DOI: 10.1021/acs.biochem.2c00705

実験手法

X-RAY DIFFRACTION (1.7 Å)