6O31
CRYSTAL STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN ALPHA-ACTININ-4
Summary for 6O31
Entry DOI | 10.2210/pdb6o31/pdb |
Descriptor | Alpha-actinin-4 (2 entities in total) |
Functional Keywords | calponin homology domain, ch domain, structural protein, actin- binding protein, actin-crosslinking, glomeruloscleros spectrin family, disease mutation, nucleus, phosphorylation |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 26713.72 |
Authors | Birrane, G.,Feng, D. (deposition date: 2019-02-25, release date: 2020-02-26, Last modification date: 2023-10-11) |
Primary citation | Feng, D.,Kumar, M.,Muntel, J.,Gurley, S.B.,Birrane, G.,Stillman, I.E.,Ding, L.,Wang, M.,Ahmed, S.,Schlondorff, J.,Alper, S.L.,Ferrante, T.,Marquez, S.L.,Ng, C.F.,Novak, R.,Ingber, D.E.,Steen, H.,Pollak, M.R. Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis. J. Am. Soc. Nephrol., 31:1479-1495, 2020 Cited by PubMed: 32540856DOI: 10.1681/ASN.2019101032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
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