6O31

CRYSTAL STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN ALPHA-ACTININ-4

6O31 の概要

• エントリーDOI: 10.2210/pdb6o31/pdb
• 分子名称: Alpha-actinin-4 (2 entities in total)
• 機能のキーワード: calponin homology domain, ch domain, structural protein, actin- binding protein, actin-crosslinking, glomeruloscleros spectrin family, disease mutation, nucleus, phosphorylation
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26713.72

構造登録者

Birrane, G.,Feng, D. (登録日: 2019-02-25, 公開日: 2020-02-26, 最終更新日: 2023-10-11)

• 主引用文献: Feng, D.,Kumar, M.,Muntel, J.,Gurley, S.B.,Birrane, G.,Stillman, I.E.,Ding, L.,Wang, M.,Ahmed, S.,Schlondorff, J.,Alper, S.L.,Ferrante, T.,Marquez, S.L.,Ng, C.F.,Novak, R.,Ingber, D.E.,Steen, H.,Pollak, M.R.; Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis.; J. Am. Soc. Nephrol., 31:1479-1495, 2020; PubMed: 32540856; DOI: 10.1681/ASN.2019101032

実験手法

X-RAY DIFFRACTION (1.51 Å)