6NZG

Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine

6NZG の概要

• エントリーDOI: 10.2210/pdb6nzg/pdb
• 分子名称: Beta-galactosidase, (1S,2R,3S,4S,5S,6R)-2-amino-3,4,5,6-tetrahydroxycyclohexane-1-carboxylic acid, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: glycoside hydrolase family 2, beta-glucuronidase, activity-based probe, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bacteroides uniformis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 202003.73

構造登録者

Pellock, S.J.,Jariwala, P.B.,Redinbo, M.R. (登録日: 2019-02-13, 公開日: 2019-12-18, 最終更新日: 2023-10-11)

• 主引用文献: Jariwala, P.B.,Pellock, S.J.,Goldfarb, D.,Cloer, E.W.,Artola, M.,Simpson, J.B.,Bhatt, A.P.,Walton, W.G.,Roberts, L.R.,Major, M.B.,Davies, G.J.,Overkleeft, H.S.,Redinbo, M.R.; Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling.; Acs Chem.Biol., 15:217-225, 2020; PubMed: 31774274; DOI: 10.1021/acschembio.9b00788

実験手法

X-RAY DIFFRACTION (2.43 Å)