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6NYQ

Crystal structure of glycosylated lysosomal membrane protein (GLMP) luminal domain bound to a Fab fragment

Summary for 6NYQ
Entry DOI10.2210/pdb6nyq/pdb
Descriptor1H3 Fab light chain, 1H3 Fab heavy chain, Glycosylated lysosomal membrane protein, ... (6 entities in total)
Functional Keywordslysosome, luminal domain, immune system
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains3
Total formula weight92888.89
Authors
Huang, C.S.,Boenig, G.,Hymowitz, S.G. (deposition date: 2019-02-12, release date: 2020-01-22, Last modification date: 2020-07-29)
Primary citationManzanillo, P.,Huang, C.S.,Boenig, G.,Calses, P.,Scherl, A.,Reichelt, M.,Katakam, A.K.,Martin, F.,Hymowitz, S.G.,Ouyang, W.
GLMP is essential for bone-marrow hematopoiesis and lysosomal glycolipid metabolism
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

221051

數據於2024-06-12公開中

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