6NUF

Structure of Calcineurin in complex with NHE1 peptide

6NUF の概要

• エントリーDOI: 10.2210/pdb6nuf/pdb
• 分子名称: Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CALCIUM ION, Calcineurin subunit B type 1, ... (11 entities in total)
• 機能のキーワード: ser/thr phosphatase, complex, hydrolase, hydrolase-calcium binding protein complex, hydrolase/calcium binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 66511.99

構造登録者

Wang, X.,Page, R.,Peti, W. (登録日: 2019-01-31, 公開日: 2019-07-03, 最終更新日: 2023-10-11)

• 主引用文献: Hendus-Altenburger, R.,Wang, X.,Sjogaard-Frich, L.M.,Pedraz-Cuesta, E.,Sheftic, S.R.,Bendsoe, A.H.,Page, R.,Kragelund, B.B.,Pedersen, S.F.,Peti, W.; Molecular basis for the binding and selective dephosphorylation of Na+/H+exchanger 1 by calcineurin.; Nat Commun, 10:3489-3489, 2019; PubMed: 31375679; DOI: 10.1038/s41467-019-11391-7

実験手法

X-RAY DIFFRACTION (1.9 Å)