6NUE

Small conformation of apo CRISPR_Csm complex

6NUE の概要

• エントリーDOI: 10.2210/pdb6nue/pdb
• EMDBエントリー: 0516 0517 0518 0519
• 分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), CRISPR system Cms protein Csm2, CRISPR type III-associated RAMP protein Csm3, ... (6 entities in total)
• 機能のキーワード: crispr, type iii-a, ssrnaase, ssdnase, hydrolase, transferase-rna complex, transferase/rna
• 由来する生物種: Streptococcus thermophilus; 詳細
• タンパク質・核酸の鎖数: 11
• 化学式量合計: 309880.12

構造登録者

Zhang, K.,Pintilie, G.,Li, S.,Zhu, Y.,Chiu, W.,Huang, Z. (登録日: 2019-01-31, 公開日: 2019-03-13, 最終更新日: 2024-03-20)

• 主引用文献: Guo, M.,Zhang, K.,Zhu, Y.,Pintilie, G.D.,Guan, X.,Li, S.,Schmid, M.F.,Ma, Z.,Chiu, W.,Huang, Z.; Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.; Cell Res., 29:305-312, 2019; PubMed: 30814678; DOI: 10.1038/s41422-019-0151-x

実験手法

ELECTRON MICROSCOPY (3.3 Å)