6NU5
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine
Summary for 6NU5
| Entry DOI | 10.2210/pdb6nu5/pdb |
| Descriptor | Pyruvate kinase PKM, CYSTEINE, OXALATE ION, ... (9 entities in total) |
| Functional Keywords | glycolysis, gene regulation, phosphotransferase, cysteine, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 121878.82 |
| Authors | Srivastava, D.,Nandi, S.,Dey, M. (deposition date: 2019-01-30, release date: 2019-08-21, Last modification date: 2023-10-11) |
| Primary citation | Srivastava, D.,Nandi, S.,Dey, M. Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2. Biochemistry, 58:3669-3682, 2019 Cited by PubMed: 31386812DOI: 10.1021/acs.biochem.9b00349 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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