6NTM
Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by A-232 in Complex with the Reactivator, HI-6
6NTM の概要
エントリーDOI | 10.2210/pdb6ntm/pdb |
関連するPDBエントリー | 6NTG 6NTH 6NTK 6NTL |
分子名称 | Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, methyl (R)-N-[(1E)-1-(diethylamino)ethylidene]-P-methylphosphonamidate, ... (6 entities in total) |
機能のキーワード | hydrolase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 121816.09 |
構造登録者 | Bester, S.M.,Guelta, M.A.,Height, J.J.,Pegan, S.D. (登録日: 2019-01-29, 公開日: 2020-07-29, 最終更新日: 2023-10-11) |
主引用文献 | Height, J.J.,Bester, S.M.,Guelta, M.A.,Bae, S.Y.,Cheung, J.,Pegan, S.D. Insights into inhibition of human acetylcholinesterase by Novichok, A-series Nerve Agents To Be Published, |
実験手法 | X-RAY DIFFRACTION (2.552 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード