6NTI

Neutron/X-ray crystal structure of AAC-VIa bound to kanamycin b

Summary for 6NTI

Entry DOI	10.2210/pdb6nti/pdb
Descriptor	Aminoglycoside N(3)-acetyltransferase, (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	acetyl transferase, neutron, transferase, transferase-antibiotic complex, transferase/antibiotic
Biological source	Enterobacteriaceae
Total number of polymer chains	1
Total formula weight	32838.26
Authors	Cuneo, M.J.,Kumar, P. (deposition date: 2019-01-29, release date: 2019-09-25, Last modification date: 2024-04-03)
Primary citation	Kumar, P.,Agarwal, P.K.,Waddell, M.B.,Mittag, T.,Serpersu, E.H.,Cuneo, M.J. Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad. Angew.Chem.Int.Ed.Engl., 58:16260-16266, 2019 Cited by PubMed: 31515870 DOI: 10.1002/anie.201908535 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION X-RAY DIFFRACTION (2.3 Å)

Structure validation