6NR5

Human LSD1 in complex with Phenelzine sulfate

6NR5 の概要

• エントリーDOI: 10.2210/pdb6nr5/pdb
• 分子名称: Lysine-specific histone demethylase 1A, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3R,4R)-5-[(4aR)-7,8-dimethyl-2,4-dioxo-5-(2-phenylethyl)-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) (2 entities in total)
• 機能のキーワード: lysine-specific histone demethylase 1a, complex, inhibitor, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 74197.55

構造登録者

Tan, A.H.Y.,Tu, W.,McCuaig, R.,Donovan, T.,Tsimbalyuk, S.,Forwood, J.K.,Rao, S. (登録日: 2019-01-22, 公開日: 2019-07-17, 最終更新日: 2024-03-13)

• 主引用文献: Tan, A.H.Y.,Tu, W.,McCuaig, R.,Hardy, K.,Donovan, T.,Tsimbalyuk, S.,Forwood, J.K.,Rao, S.; Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer.; Front Immunol, 10:1351-1351, 2019; PubMed: 31249575; DOI: 10.3389/fimmu.2019.01351

実験手法