6NLF

1.45 A resolution structure of apo BfrB from Pseudomonas aeruginosa

Summary for 6NLF

• Entry DOI: 10.2210/pdb6nlf/pdb
• Descriptor: Ferroxidase, POTASSIUM ION (3 entities in total)
• Functional Keywords: electron transport, iron storage, iron binding, iron mobilization, protein-protein interaction, oxidoreductase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
• Total number of polymer chains: 12
• Total formula weight: 223079.31

Authors

Lovell, S.,Punchi-Hewage, A.,Battaile, K.P.,Yao, H.,Nammalwar, B.,Gnanasekaran, K.K.,Bunce, R.A.,Reitz, A.B.,Rivera, M. (deposition date: 2019-01-08, release date: 2019-05-08, Last modification date: 2023-10-11)

• Primary citation: Punchi Hewage, A.N.D.,Yao, H.,Nammalwar, B.,Gnanasekaran, K.K.,Lovell, S.,Bunce, R.A.,Eshelman, K.,Phaniraj, S.M.,Lee, M.M.,Peterson, B.R.,Battaile, K.P.,Reitz, A.B.,Rivera, M.; Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity.; J.Am.Chem.Soc., 141:8171-8184, 2019; PubMed: 31038945; DOI: 10.1021/jacs.9b00394

Experimental method

X-RAY DIFFRACTION (1.45 Å)