6NLE

X-ray structure of LeuT with V269 deletion

Summary for 6NLE

Entry DOI	10.2210/pdb6nle/pdb
Descriptor	Na(+):neurotransmitter symporter (Snf family), LEUCINE, SODIUM ION, ... (9 entities in total)
Functional Keywords	leut, membrane protein
Biological source	Aquifex aeolicus (strain VF5)
Total number of polymer chains	1
Total formula weight	57899.41
Authors	Navratna, V.,Yang, D.,Gouaux, E. (deposition date: 2019-01-08, release date: 2020-01-15, Last modification date: 2024-03-13)
Primary citation	Campbell, N.G.,Shekar, A.,Aguilar, J.I.,Peng, D.,Navratna, V.,Yang, D.,Morley, A.N.,Duran, A.M.,Galli, G.,O'Grady, B.,Ramachandran, R.,Sutcliffe, J.S.,Sitte, H.H.,Erreger, K.,Meiler, J.,Stockner, T.,Bellan, L.M.,Matthies, H.J.G.,Gouaux, E.,Mchaourab, H.S.,Galli, A. Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion inSLC6A3. Proc.Natl.Acad.Sci.USA, 116:3853-3862, 2019 Cited by PubMed: 30755521 DOI: 10.1073/pnas.1816247116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.615 Å)

Structure validation