6NKM
Structure of PhqE D166N Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and substrate
Summary for 6NKM
Entry DOI | 10.2210/pdb6nkm/pdb |
Related | 6NKH 6NKK |
Descriptor | Short chain dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-{[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methyl}-8H-pyrrolo[1,2-a]pyrazin-5-ium-1-olate, ... (4 entities in total) |
Functional Keywords | reductase, diels-alderase, oxidoreductase |
Biological source | Penicillium fellutanum |
Total number of polymer chains | 6 |
Total formula weight | 170113.60 |
Authors | Newmister, S.A.,Dan, Q.,Smith, J.L.,Sherman, D.H. (deposition date: 2019-01-07, release date: 2019-10-09, Last modification date: 2024-03-13) |
Primary citation | Dan, Q.,Newmister, S.A.,Klas, K.R.,Fraley, A.E.,McAfoos, T.J.,Somoza, A.D.,Sunderhaus, J.D.,Ye, Y.,Shende, V.V.,Yu, F.,Sanders, J.N.,Brown, W.C.,Zhao, L.,Paton, R.S.,Houk, K.N.,Smith, J.L.,Sherman, D.H.,Williams, R.M. Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase. Nat.Chem., 11:972-980, 2019 Cited by PubMed: 31548667DOI: 10.1038/s41557-019-0326-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.896 Å) |
Structure validation
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