6NK1
EphA2 LBD in complex with bA-WLA-YRPKbio peptide
Summary for 6NK1
Entry DOI | 10.2210/pdb6nk1/pdb |
Descriptor | Ephrin type-A receptor 2, bA-WLA-YRPKbio, ACETATE ION, ... (5 entities in total) |
Functional Keywords | protein-peptide interaction, kinase, ephrin, eph receptor, drug development, signaling protein, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 46218.21 |
Authors | Lechtenberg, B.C.,Pasquale, E.B. (deposition date: 2019-01-04, release date: 2019-05-01, Last modification date: 2023-10-11) |
Primary citation | Gomez-Soler, M.,Petersen Gehring, M.,Lechtenberg, B.C.,Zapata-Mercado, E.,Hristova, K.,Pasquale, E.B. Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling. J.Biol.Chem., 294:8791-8805, 2019 Cited by PubMed: 31015204DOI: 10.1074/jbc.RA119.008213 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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