6NHW

Structure of the transmembrane domain of the Death Receptor 5 - Dimer of Trimer

Summary for 6NHW

Entry DOI	10.2210/pdb6nhw/pdb
NMR Information	BMRB: 30553
Descriptor	Tumor necrosis factor receptor superfamily member 10B (1 entity in total)
Functional Keywords	death receptor 5, transmembrane helix oligomer, transmembrane helix mediated signaling, preligand autoinhibition, immune system
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	22354.19
Authors	Chou, J.J.,Pan, L.,Fu, Q.,Zhao, L.,Chen, W.,Piai, A.,Fu, T.,Wu, H. (deposition date: 2018-12-24, release date: 2019-02-27, Last modification date: 2023-06-14)
Primary citation	Pan, L.,Fu, T.M.,Zhao, W.,Zhao, L.,Chen, W.,Qiu, C.,Liu, W.,Liu, Z.,Piai, A.,Fu, Q.,Chen, S.,Wu, H.,Chou, J.J. Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling. Cell, 176:1477-1489.e14, 2019 Cited by PubMed: 30827683 DOI: 10.1016/j.cell.2019.02.001 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation