6NFN
Fab fragment of anti-cocaine antibody h2E2 bound to benzoylecgonine
Summary for 6NFN
Entry DOI | 10.2210/pdb6nfn/pdb |
Related | 6NEX |
Descriptor | Fab h2E2 light chain, Fab h2E2 heavy chain, 3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID, ... (8 entities in total) |
Functional Keywords | fab-benzoylecgonine complex fab fragment anti-cocaine antibody humanized mab h2e2, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 16 |
Total formula weight | 375002.79 |
Authors | Pokkuluri, P.R.,Tan, K. (deposition date: 2018-12-20, release date: 2019-11-20, Last modification date: 2023-10-11) |
Primary citation | Tan, K.,Zhou, M.,Ahrendt, A.J.,Duke, N.E.C.,Tabaja, N.,Ball, W.J.,Kirley, T.L.,Norman, A.B.,Joachimiak, A.,Schiffer, M.,Wilton, R.,Pokkuluri, P.R. Structural analysis of free and liganded forms of the Fab fragment of a high-affinity anti-cocaine antibody, h2E2. Acta Crystallogr.,Sect.F, 75:697-706, 2019 Cited by PubMed: 31702583DOI: 10.1107/S2053230X19013608 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.63 Å) |
Structure validation
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