6NFN

Fab fragment of anti-cocaine antibody h2E2 bound to benzoylecgonine

Summary for 6NFN

• Entry DOI: 10.2210/pdb6nfn/pdb
• Related: 6NEX
• Descriptor: Fab h2E2 light chain, Fab h2E2 heavy chain, 3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID, ... (8 entities in total)
• Functional Keywords: fab-benzoylecgonine complex fab fragment anti-cocaine antibody humanized mab h2e2, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 16
• Total formula weight: 375002.79

Authors

Pokkuluri, P.R.,Tan, K. (deposition date: 2018-12-20, release date: 2019-11-20, Last modification date: 2023-10-11)

• Primary citation: Tan, K.,Zhou, M.,Ahrendt, A.J.,Duke, N.E.C.,Tabaja, N.,Ball, W.J.,Kirley, T.L.,Norman, A.B.,Joachimiak, A.,Schiffer, M.,Wilton, R.,Pokkuluri, P.R.; Structural analysis of free and liganded forms of the Fab fragment of a high-affinity anti-cocaine antibody, h2E2.; Acta Crystallogr.,Sect.F, 75:697-706, 2019; PubMed: 31702583; DOI: 10.1107/S2053230X19013608

Experimental method

X-RAY DIFFRACTION (2.63 Å)