6NEA

Human Acetylcholinesterase in complex with reactivator, HLo7

6NEA の概要

• エントリーDOI: 10.2210/pdb6nea/pdb
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 121746.94

構造登録者

Bester, S.M.,McGuire, J.,Height, J.J.,Pegan, S.D. (登録日: 2018-12-17, 公開日: 2019-06-12, 最終更新日: 2023-10-11)

• 主引用文献: Hsu, F.L.,Bae, S.Y.,McGuire, J.,Anderson, D.R.,Bester, S.M.,Height, J.J.,Pegan, S.D.,Walz, A.J.; Synthesis and Molecular Properties of Nerve Agent Reactivator HLo-7 Dimethanesulfonate.; Acs Med.Chem.Lett., 10:761-766, 2019; PubMed: 31097996; DOI: 10.1021/acsmedchemlett.9b00021

実験手法

X-RAY DIFFRACTION (2.419 Å)