6NEA

Human Acetylcholinesterase in complex with reactivator, HLo7

6NEA の概要

分子名称Acetylcholinesterase, ALPHA-L-FUCOSE, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
機能のキーワードhydrolase
由来する生物種Homo sapiens (Human)
ポリマー鎖数2
分子量合計121819
構造登録者
Bester, S.M.,McGuire, J.,Height, J.J.,Pegan, S.D. (登録日: 2018-12-17, 公開日: 2019-06-12)
主引用文献
Hsu, F.L.,Bae, S.Y.,McGuire, J.,Anderson, D.R.,Bester, S.M.,Height, J.J.,Pegan, S.D.,Walz, A.J.
Synthesis and Molecular Properties of Nerve Agent Reactivator HLo-7 Dimethanesulfonate.
Acs Med.Chem.Lett., 10:761-766, 2019
PubMed: 31097996 (主引用文献が同じPDBエントリー)
DOI: 10.1021/acsmedchemlett.9b00021
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.419 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20530 1.6% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード