6ND5

Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution

これはPDB形式変換不可エントリーです。

6ND5 の概要

• エントリーDOI: 10.2210/pdb6nd5/pdb
• 分子名称: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (61 entities in total)
• 機能のキーワード: chloramphenicol, erythromycin, competition, antibiotic, 70s ribosome, inhibition of translation, peptidyl transferase center, nascent peptide exit tunnel, ribosome, ribosome-antibiotic complex, ribosome/antibiotic
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 112
• 化学式量合計: 4571677.03

構造登録者

Svetlov, M.S.,Plessa, E.,Chen, C.-W.,Bougas, A.,Krokidis, M.G.,Dinos, G.P.,Polikanov, Y.S. (登録日: 2018-12-13, 公開日: 2019-03-20, 最終更新日: 2023-11-15)

• 主引用文献: Svetlov, M.S.,Plessa, E.,Chen, C.W.,Bougas, A.,Krokidis, M.G.,Dinos, G.P.,Polikanov, Y.S.; High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.; RNA, 25:600-606, 2019; PubMed: 30733327; DOI: 10.1261/rna.069260.118

実験手法

X-RAY DIFFRACTION (2.6 Å)