6NB3

MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1)

6NB3 の概要

• エントリーDOI: 10.2210/pdb6nb3/pdb
• 関連するPDBエントリー: 6NB4 6NB5 6NB6 6NB7 6NB8
• EMDBエントリー: 0401 0402 0403 0404
• 分子名称: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 light chain, ... (10 entities in total)
• 機能のキーワード: coronavirus spike glycoprotein, mers-cov, sars-cov, human neutralizing antibodies, structural genomics, seattle structural genomics center for infectious disease, ssgcid, virus
• 由来する生物種: Middle East respiratory syndrome-related coronavirus; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 528519.22

構造登録者

Walls, A.C.,Xiong, X.,Park, Y.J.,Tortorici, M.A.,Snijder, S.,Quispe, J.,Cameroni, E.,Gopal, R.,Mian, D.,Lanzavecchia, A.,Zambon, M.,Rey, F.A.,Corti, D.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2018-12-06, 公開日: 2019-02-06, 最終更新日: 2020-07-29)

• 主引用文献: Walls, A.C.,Xiong, X.,Park, Y.J.,Tortorici, M.A.,Snijder, J.,Quispe, J.,Cameroni, E.,Gopal, R.,Dai, M.,Lanzavecchia, A.,Zambon, M.,Rey, F.A.,Corti, D.,Veesler, D.; Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.; Cell, 176:1026-1039.e15, 2019; PubMed: 30712865; DOI: 10.1016/j.cell.2018.12.028

実験手法

ELECTRON MICROSCOPY (3.5 Å)