6NAE

Crystal Structure of Ebola zaire GP protein with bound ARN0074898

6NAE の概要

• エントリーDOI: 10.2210/pdb6nae/pdb
• 分子名称: Envelope glycoprotein,Envelope glycoprotein,Envelope glycoprotein, Envelope glycoprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: ssgcid, ebola zaire, glycoprotein, structural genomics, seattle structural genomics center for infectious disease, viral protein
• 由来する生物種: Zaire ebolavirus (strain Mayinga-76) (ZEBOV); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57847.70

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2018-12-05, 公開日: 2019-12-11, 最終更新日: 2023-10-11)

• 主引用文献: Plewe, M.B.,Sokolova, N.V.,Gantla, V.R.,Brown, E.R.,Naik, S.,Fetsko, A.,Lorimer, D.D.,Dranow, D.M.,Smutney, H.,Bullen, J.,Sidhu, R.,Master, A.,Wang, J.,Kallel, E.A.,Zhang, L.,Kalveram, B.,Freiberg, A.N.,Henkel, G.,McCormack, K.; Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.; Acs Med.Chem.Lett., 11:1160-1167, 2020; PubMed: 32550996; DOI: 10.1021/acsmedchemlett.0c00025

実験手法

X-RAY DIFFRACTION (2.75 Å)