6N9P
Discovery of affinity-based probes for Btk occupancy assay
Summary for 6N9P
Entry DOI | 10.2210/pdb6n9p/pdb |
Descriptor | Tyrosine-protein kinase BTK, N-(3-{[2-amino-3-(4-phenoxyphenyl)pyridin-4-yl]oxy}phenyl)propanamide (3 entities in total) |
Functional Keywords | btk tool compound, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 32023.77 |
Authors | |
Primary citation | Qiu, H.,Caldwell, R.,Liu-Bujalski, L.,Goutopoulos, A.,Jones, R.,Potnick, J.,Sherer, B.,Bender, A.,Grenningloh, R.,Xu, D.,Gardberg, A.,Mochalkin, I.,Johnson, T.,Viacava Follis, A.,Head, J.,Morandi, F. Discovery of Affinity-Based Probes for Btk Occupancy Assays. ChemMedChem, 14:217-223, 2019 Cited by PubMed: 30521698DOI: 10.1002/cmdc.201800714 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
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