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6N9P

Discovery of affinity-based probes for Btk occupancy assay

Summary for 6N9P
Entry DOI10.2210/pdb6n9p/pdb
DescriptorTyrosine-protein kinase BTK, N-(3-{[2-amino-3-(4-phenoxyphenyl)pyridin-4-yl]oxy}phenyl)propanamide (3 entities in total)
Functional Keywordsbtk tool compound, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight32023.77
Authors
Mochalkin, I. (deposition date: 2018-12-03, release date: 2019-02-06)
Primary citationQiu, H.,Caldwell, R.,Liu-Bujalski, L.,Goutopoulos, A.,Jones, R.,Potnick, J.,Sherer, B.,Bender, A.,Grenningloh, R.,Xu, D.,Gardberg, A.,Mochalkin, I.,Johnson, T.,Viacava Follis, A.,Head, J.,Morandi, F.
Discovery of Affinity-Based Probes for Btk Occupancy Assays.
ChemMedChem, 14:217-223, 2019
Cited by
PubMed: 30521698
DOI: 10.1002/cmdc.201800714
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.23 Å)
Structure validation

217705

건을2024-03-27부터공개중

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