6N5W
Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains
Summary for 6N5W
Entry DOI | 10.2210/pdb6n5w/pdb |
Descriptor | Potassium voltage-gated channel subfamily KQT member 4, Calmodulin-1, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | ion channel, calmodulin, kcnq4 peptides, complex, metal binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 23216.27 |
Authors | Taylor, A.B.,Archer, C.R.,Shapiro, M.S. (deposition date: 2018-11-22, release date: 2019-03-13, Last modification date: 2023-10-11) |
Primary citation | Archer, C.R.,Enslow, B.T.,Taylor, A.B.,De la Rosa, V.,Bhattacharya, A.,Shapiro, M.S. A mutually induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K+channels. J. Biol. Chem., 294:6094-6112, 2019 Cited by PubMed: 30808708DOI: 10.1074/jbc.RA118.006857 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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