6N5W

Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains

6N5W の概要

• エントリーDOI: 10.2210/pdb6n5w/pdb
• 分子名称: Potassium voltage-gated channel subfamily KQT member 4, Calmodulin-1, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: ion channel, calmodulin, kcnq4 peptides, complex, metal binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 23216.27

構造登録者

Taylor, A.B.,Archer, C.R.,Shapiro, M.S. (登録日: 2018-11-22, 公開日: 2019-03-13, 最終更新日: 2023-10-11)

• 主引用文献: Archer, C.R.,Enslow, B.T.,Taylor, A.B.,De la Rosa, V.,Bhattacharya, A.,Shapiro, M.S.; A mutually induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K+channels.; J. Biol. Chem., 294:6094-6112, 2019; PubMed: 30808708; DOI: 10.1074/jbc.RA118.006857

実験手法

X-RAY DIFFRACTION (2.15 Å)