6N4T
Crystal structure of Matriptase1 in complex with a peptidomimetic benzothiazole
Summary for 6N4T
| Entry DOI | 10.2210/pdb6n4t/pdb |
| Related PRD ID | PRD_002338 |
| Descriptor | Suppressor of tumorigenicity 14 protein, MAGNESIUM ION, ETHANOL, ... (7 entities in total) |
| Functional Keywords | inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 27642.46 |
| Authors | Campobasso, N. (deposition date: 2018-11-20, release date: 2019-10-02, Last modification date: 2019-12-04) |
| Primary citation | Beliveau, F.,Tarkar, A.,Dion, S.P.,Desilets, A.,Ghinet, M.G.,Boudreault, P.L.,St-Georges, C.,Marsault, E.,Paone, D.,Collins, J.,Macphee, C.H.,Campobasso, N.,Groy, A.,Cottom, J.,Ouellette, M.,Pope, A.J.,Leduc, R. Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes. Cell Chem Biol, 26:1559-1572.e9, 2019 Cited by PubMed: 31543462DOI: 10.1016/j.chembiol.2019.09.004 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.945 Å) |
Structure validation
Download full validation report
