6N4P

RQEFEV, crystal structure of the N-terminal segment RQEFEV from protein tau

6N4P の概要

• エントリーDOI: 10.2210/pdb6n4p/pdb
• 分子名称: Microtubule-associated protein tau (2 entities in total)
• 機能のキーワード: amyloid, tau, alzheimer's disease, tauopathy, mapt, protein fibril
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 1615.74

構造登録者

Eisenberg, D.S.,Boyer, D.R. (登録日: 2018-11-19, 公開日: 2019-11-20, 最終更新日: 2024-04-03)

• 主引用文献: Boyer, D.R.,Eisenberg, D.S.; A structure-based model for the electrostatic interaction of the N-terminus of protein tau with the fibril core of Alzheimer's Disease filaments; Biorxiv, 2021; DOI: 10.1101/484279

実験手法

X-RAY DIFFRACTION (1.851 Å)